A guanosine analog antiviral drug that acts as an antimetabolite. Acyclovir is used for the treatment of herpes simplex virus infections, varicella zoster (chickenpox) and herpes zoster (shingles). Acyclovir has also been investigated for the treatment of herpes labialis applied using an iontophoretic device. Currently approved drugs for the treatment of herpes labialis (cold sores) exhibit low levels of efficacy due to the limited ability of the drugs to penetrate the skin to the site where the herpes virus is replicating. Iontophoresis uses electric current to enhance the delivery of drugs through the skin.
Acyclovir (INN) or acyclovir (USAN, former BAN) is a synthetic deoxyguanosine analog and it is the prototype antiviral agent that is activated by viral thymidine kinase. The selective activity of acyclovir is due to its affinity for the thymidine kinase enzyme encoded by HSV and VZV. EC50 value of acyclovir against clinical herpes virus isolates was 1.3 μM (range: < 0.56 to 3.3 μM).
Acyclovir may cause nephrotoxicity (crystallization of acyclovir within renal tubules, elevation of serum creatinine, transient), and neurotoxicity (coma, hallucinations, lethargy, seizures, tremors). Nephrotoxicity and neurotoxicity usually resolve after cessation of acyclovir therapy. However, there is no well-defined relationship between acyclovir concentrations in the blood and these adverse effects.
Imprints
Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: N943 400
Color: Blue
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: WATSON 335
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: N947 800
Color: White
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: CTI 112
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: N 940 200
Color: Blue
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: RX504
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: CTI 113
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: Logo 5306
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: A02 400
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: WATSON 336
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: Logo 5307
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: MYLAN 302
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: Logo 4267 400
Color: White
Shape: Round
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: RX505
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: 200 CTI 111
Color: Blue & White
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: APO 042
Color: Turquoise & White
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: WATSON Acyclovir 200
Color: Blue
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: MYLAN 2200 MYLAN 2200
Color: Purple
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: Logo 4268 800
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: RX652 RX652
Color: White
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: 511 ACYCLOVIR 200 Mg
Color: White
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: HP 146 HP 146
Color: Blue / Green
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: ACY 800
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: G 0036
Color: White
Shape: Five-sided
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: Zenith 4266 200
Color: White
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: A 03 800
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: G 0037
Color: Blue
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: A05 200
Color: Blue
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: G 0034
Color: Blue
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: R607
Color: Green
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: R-605 R-605
Color: Green
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: 511 A77
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: HP 228
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: J 50
Color: Blue
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: 93 044
Color: Blue
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: ACY200
Color: White
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 400 Mg
Pill Imprint: CP114 400
Color: White
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: CP113 800
Color: Blue
Shape: Elliptical / Oval
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Drug: Acyclovir
Strength: 200 Mg
Pill Imprint: CP115 200
Color: Blue
Shape: Capsule-shape
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Drug: Acyclovir
Strength: 800 Mg
Pill Imprint: 792
Color: White
Shape: Elliptical / Oval
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