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Bactrim

A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by sulfonamides and the bactrim-sulfamethoxazole combination is the form most often used. It is sometimes used alone as an antimalarial. Bactrim resistance has been reported.

Bactrim is a pyrimidine analogue that disrupts folate synthesis, an essential part of the thymidine synthesis pathway. Inhibition of the enzyme starves the bacteria of nucleotides necessary for DNA replication.The drug, therefore, exhibits bactericidal activity.

LD50=4850 (orally in mice)

Imprints


Drug: Bactrim
Strength: 400 Mg / 80 Mg
Pill Imprint: BACTRIM
Color: White
Shape: Round

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Drug: Bactrim
Strength: 400 Mg / 80 Mg
Pill Imprint: BACTRIM
Color: Green
Shape: Elliptical / Oval

View Images & Details
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