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Claritin

Claritin is a derivative of azatadine and a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (histamine H1 antagonists) it lacks central nervous system depressing effects such as drowsiness.

Claritin is a long acting second generation antihistamine that is similar in structure to cyproheptadine and azatadine. The pharmacology of claritin is similar to other antihistamines, but unlike other H1-blockers, loratidine is shown to exhibit competitive, specific, and selective antagonism of H1 receptors. The exact mechanism of this interaction is unknown, but disposition of the drug suggests that claritin’s prolonged antagonism of histamine may be due to the drug’s slow dissociation from the receptor or the formation of the active metabolite, desclaritin. Claritin does not penetrate the CNS effectively and has a low affinity for CNS H1-receptors.

somnolence, tachycardia, and headache LD50=mg/kg (orally in rat)

Imprints


Drug: Claritin
Strength: 10 Mg
Pill Imprint: CLARITIN 10 458
Color: White
Shape: Round

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Drug: Claritin
Strength: 10 Mg
Pill Imprint: C-10
Color: Blue
Shape: Elliptical / Oval

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Drug: Claritin
Strength: 5 Mg
Pill Imprint: CLARITIN 5
Color: Purple
Shape: Round

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