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Doxazosin

Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors. It may be used to mild to moderate hypertension and in the management of symptomatic benign prostatic hyperplasia (BPH ). α1-Receptors mediate contraction and hypertrophic growth of smooth muscle cells. Antagonism of these receptors leads to smooth muscle relaxation in the peripheral vasculature and prostate gland.

Doxazosin is an alpha-adrenergic blocking agent used to treat hypertension and benign prostatic hyperplasia. Accordingly, Doxazosin is a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors. In the human prostate, Doxazosin antagonizes phenylephrine (alpha1 agonist)-induced contractions, in vitro, and binds with high affinity to the alpha1c adrenoceptor, which is thought to be the predominant functional type in the prostate. Studies in normal human subjects have shown that Doxazosin competitively antagonized the pressor effects of phenylephrine (an alpha1 agonist) and the systolic pressor effect of norepinephrine. The antihypertensive effect of Doxazosin results from a decrease in systemic vascular resistance and the parent compound Doxazosin is primarily responsible for the antihypertensive activity.

Symptoms of overdose include hypotension. Oral LD50 is greater than 1000 mg/kg in mice and rats.

Imprints


Drug: Doxazosin
Strength: 4 Mg
Pill Imprint: M D11
Color: Blue
Shape: Round

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Drug: Doxazosin
Strength: 4 Mg
Pill Imprint: N 596 4
Color: White
Shape: Four-sided

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Drug: Doxazosin
Strength: 2 Mg
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Drug: Doxazosin
Strength: 2 Mg
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Drug: Doxazosin
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Drug: Doxazosin
Strength: 4 Mg
Pill Imprint: APO 095
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Drug: Doxazosin
Strength: 1 Mg
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Drug: Doxazosin
Strength: 8 Mg
Pill Imprint: M D12
Color: Purple
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Drug: Doxazosin
Strength: 2 Mg
Pill Imprint: APO 094
Color: White
Shape: Capsule-shape

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Drug: Doxazosin
Strength: 8 Mg
Pill Imprint: APO 096
Color: White
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Drug: Doxazosin
Strength: 1 Mg
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Drug: Doxazosin
Strength: 1 Mg
Pill Imprint: APO 093
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Drug: Doxazosin
Strength: 4 Mg
Pill Imprint: ML P18 4 Mg
Color: Orange
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Drug: Doxazosin
Strength: 4 Mg
Pill Imprint: PLIVA 653
Color: Orange
Shape: Round

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Drug: Doxazosin
Strength: 2 Mg
Pill Imprint: ML P17 2 Mg
Color: Yellow
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Strength: 8 Mg
Pill Imprint: ML P19 8 Mg
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Drug: Doxazosin
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Pill Imprint: 4 Mg ETH 268
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Strength: 1 Mg
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Strength: 1 Mg
Pill Imprint: ML P16 1 Mg
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Strength: 8 Mg
Pill Imprint: PLIVA 654
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Drug: Doxazosin
Strength: 1 Mg
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Strength: 1 Mg
Pill Imprint: TV 590
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Strength: 2 Mg
Pill Imprint: 2 Mg ETH267
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Strength: 8 Mg
Pill Imprint: ETH269 8 Mg
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Drug: Doxazosin
Strength: 4 Mg
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Drug: Doxazosin
Strength: 8 Mg
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Drug: Doxazosin
Strength: 2 Mg
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Strength: 8 Mg
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Strength: 2 Mg
Pill Imprint: R643
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Strength: 4 Mg
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Strength: 2 Mg
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Strength: 2 Mg
Pill Imprint: DX 2 G
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Drug: Doxazosin
Strength: 2 Mg
Pill Imprint: 652 SL
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Drug: Doxazosin
Strength: 4 Mg
Pill Imprint: DX 4 G
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Strength: 8 Mg
Pill Imprint: DX 8 G
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Strength: 2 Mg
Pill Imprint: CARDURA 2 Mg
Color: Yellow
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Strength: 4 Mg
Pill Imprint: CARDURA 4 Mg
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Strength: 8 Mg
Pill Imprint: CARDURA 8 Mg
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Strength: 2 Mg
Pill Imprint: C3
Color: Yellow
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Strength: 4 Mg
Pill Imprint: C4
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Strength: 8 Mg
Pill Imprint: C4
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Strength: 2 Mg
Pill Imprint: CARDURA 2 Mg
Color: Yellow
Shape: Elliptical / Oval

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Strength: 4 Mg
Pill Imprint: CARDURA 4 Mg
Color: Orange
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Strength: 1 Mg
Pill Imprint: CARDURA 1 Mg
Color: White
Shape: Elliptical / Oval

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Drug: Doxazosin
Strength: 8 Mg
Pill Imprint: CARDURA 8 Mg
Color: Green
Shape: Elliptical / Oval

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Drug: Doxazosin
Strength: 4 Mg
Pill Imprint: CXL 4
Color: White
Shape: Round

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Drug: Doxazosin
Strength: 8 Mg
Pill Imprint: CXL 8
Color: White
Shape: Round

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