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Excedrin

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Excedrin’s most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes smooth muscle, stimulates cardiac muscle, stimulates diuresis, and appears to be useful in the treatment of some types of headache. Several cellular actions of excedrin have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide phosphodiesterases, antagonism of adenosine receptors, and modulation of intracellular calcium handling.

Excedrin, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, excedrin is used to treat migraine and other headache types. Over the counter, excedrin is available to treat drowsiness or mild water-weight gain.

LD50=127 mg/kg (orally in mice)

Imprints


Drug: Excedrin
Strength: Acetaminophen 500 Mg / Caffeine 65 Mg
Pill Imprint: AFE
Color: Red
Shape: Elliptical / Oval

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Drug: Excedrin
Strength: 250 Mg / 250 Mg / 65 Mg
Pill Imprint: E
Color: White
Shape: Capsule-shape

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Drug: Excedrin
Strength: 250 Mg / 250 Mg / 65 Mg
Pill Imprint: E
Color: White
Shape: Round

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Drug: Excedrin
Strength: 500-65 Mg
Pill Imprint: ETH
Color: Red
Shape: Capsule-shape

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Drug: Excedrin
Strength: Acetaminophen 250 Mg / Aspirin 250 Mg
Pill Imprint: EBB
Color: Green
Shape: Capsule-shape

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Drug: Excedrin
Strength: 250 Mg / 250 Mg / 65 Mg
Pill Imprint: E
Color: Green / White
Shape: Round

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Drug: Excedrin
Strength: 500 Mg / 38 Mg
Pill Imprint: PM
Color: Blue
Shape: Round

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Drug: Excedrin
Strength: 250 Mg / 250 Mg / 65 Mg
Pill Imprint: E
Color: Green
Shape: Capsule-shape

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Drug: Excedrin
Strength: 500 Mg / 38 Mg
Pill Imprint: PM
Color: Blue
Shape: Capsule-shape

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Drug: Excedrin
Strength: 500-65 Mg
Pill Imprint: ETH
Color: Red
Shape: Round

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Drug: Excedrin
Strength: Acetaminophen 250 Mg / Aspirin 250 Mg / Caffeine 6
Pill Imprint: EX
Color: White
Shape: Capsule-shape

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Drug: Excedrin
Strength: Acetaminophen 250 Mg / Aspirin 250 Mg / Caffeine 6
Pill Imprint: Ex
Color: White
Shape: Capsule-shape

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Drug: Excedrin
Strength: Acetaminophen 250 Mg / Aspirin 250 Mg / Caffeine 6
Pill Imprint: E
Color: Green & White
Shape: Round

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Drug: Excedrin
Strength: Acetaminophen 325 Mg / Caffeine 65 Mg
Pill Imprint: LDE
Color: Yellow
Shape: Capsule-shape

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Drug: Excedrin
Strength: Acetaminophen 250 Mg / Aspirin 250 Mg / Diphenhydr
Pill Imprint: EXPM
Color: Blue
Shape: Capsule-shape

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Drug: Excedrin
Strength: Acetaminophen 250 Mg / Aspirin 250 Mg / Diphenhydr
Pill Imprint: EXPM
Color: Blue
Shape: Capsule-shape

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