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Flexeril

Flexeril is a skeletal muscle relaxant and a central nervous system (CNS ) depressant. Flexeril acts on the locus coeruleus where it results in increased norepinephrine release, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the ventral horn of the spinal cord. It is structurally similar to Amitriptyline, differing by only one double bond.

Flexeril, closely related to the antidepressant amitriptyline, is used as a skeletal muscle relaxant to reduce pain and tenderness and improve mobility. Unlike dantrolene, flexeril cannot be used to treat muscle spasm secondary to cerebral or spinal cord disease.

Oral mouse and rat LD50 are 338 mg/kg and 425 mg/kg respectively. Signs of overdose include agitation, coma, confusion, congestive heart failure, convulsions, dilated pupils, disturbed concentration, drowsiness, hallucinations, high or low temperature, increased heartbeats, irregular heart rhythms, muscle stiffness, overactive reflexes, severe low blood pressure, stupor, and vomiting.

Imprints


Drug: Flexeril
Strength: 10 Mg
Pill Imprint: FLEXERIL MSD 931
Color: Yellow
Shape: Five-sided

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Drug: Flexeril
Strength: 5 Mg
Pill Imprint: FLEXERIL
Color: Orange
Shape: Five-sided

View Images & Details

Drug: Flexeril
Strength: 10 Mg
Pill Imprint: FLEXERIL MSD 931
Color: Yellow
Shape: Five-sided

View Images & Details

Drug: Flexeril
Strength: 5 Mg
Pill Imprint: FLEXERIL
Color: Orange
Shape: Five-sided

View Images & Details
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