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Geodon

Geodon (marketed as Geodon, Zeldox) was the fifth atypical antipsychotic to gain FDA approval (February 2001). Geodon is Food and Drug Administration (FDA ) approved for the treatment of schizophrenia, and the intramuscular injection form of geodon is approved for acute agitation in schizophrenic patients. Geodon has also received approval for acute treatment of mania associated with bipolar disorder.

Geodon is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Geodon is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), dopamine Type 2 (D2), 1 and 2 adrenergic, and H1 histaminergic receptors. Geodon acts as an antagonist at other receptors, but with lower potency. Antagonism at receptors other than dopamine and 5HT2 with similar receptor affinities may explain some of the other therapeutic and side effects of Geodon. Geodon’s antagonism of muscarinic M1-5 receptors may explain its anticholinergic effects. Geodon’s antagonism of histamine H1 receptors may explain the somnolence observed with this drug. Geodon’s antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. Geodon functions as an antagonist at the Dopamine D2 , 5HT-2A , and 5HT-1D receptors, and as an agonist at the 5HT-1A receptor. Geodon also inhibits synaptic reuptake of serotonin and norepinephrine.

Imprints


Drug: Geodon
Strength: 80 Mg
Pill Imprint: PFIZER 399 PFIZER 399
Color: Blue & White
Shape: Capsule-shape

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Drug: Geodon
Strength: 60 Mg
Pill Imprint: PFIZER 398 PFIZER 398
Color: White
Shape: Capsule-shape

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Drug: Geodon
Strength: 40 Mg
Pill Imprint: PFIZER 397 PFIZER 397
Color: Blue
Shape: Capsule-shape

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Drug: Geodon
Strength: 20 Mg
Pill Imprint: PFIZER 396 PFIZER 396
Color: Blue & White
Shape: Capsule-shape

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