Hytrin is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH ). It also acts to lower blood pressure, so it is a drug of choice for men with hypertension and prostate enlargement. It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls.
Hytrin, classified as a quinazoline, is similar to doxazosin and prazosin. As an α-adrenergic blocking agent, hytrin is used to treat hypertension and BPH. Hytrin produces vasodilation and reduces peripheral resistance but in general has only a slight effect on cardiac output. The antihypertensive effect with chronic dosing is not usually accompanied by reflex tachycardia.
LD50=259.3mg/kg (IV in mice)