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Loratadine

Loratadine is a derivative of azatadine and a second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (histamine H1 antagonists) it lacks central nervous system depressing effects such as drowsiness.

Loratadine is a long acting second generation antihistamine that is similar in structure to cyproheptadine and azatadine. The pharmacology of loratadine is similar to other antihistamines, but unlike other H1-blockers, loratidine is shown to exhibit competitive, specific, and selective antagonism of H1 receptors. The exact mechanism of this interaction is unknown, but disposition of the drug suggests that loratadine’s prolonged antagonism of histamine may be due to the drug’s slow dissociation from the receptor or the formation of the active metabolite, desloratadine. Loratadine does not penetrate the CNS effectively and has a low affinity for CNS H1-receptors.

somnolence, tachycardia, and headache LD50=mg/kg (orally in rat)

Imprints


Drug: Loratadine
Strength: 10 Mg
Pill Imprint: CLARITIN 10 458
Color: White
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: C-10
Color: Blue
Shape: Elliptical / Oval

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: CLARITIN 5
Color: Purple
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: C
Color: White
Shape: Round

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: C
Color: Purple
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: C10
Color: White
Shape: Round

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: C5
Color: White
Shape: Round

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Drug: Loratadine
Strength: 10 Mg / 240 Mg
Pill Imprint: RX724
Color: White
Shape: Elliptical / Oval

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Drug: Loratadine
Strength: 10 Mg / 240 Mg
Pill Imprint: Andrx 605
Color: White
Shape: Elliptical / Oval

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Drug: Loratadine
Strength: 10 Mg / 240 Mg
Pill Imprint: L724
Color: White
Shape: Elliptical / Oval

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: L612
Color: White
Shape: Elliptical / Oval

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: GG 296
Color: White
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: RX 526
Color: White
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: APO LOR 10
Color: White
Shape: Elliptical / Oval

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: LOR 10
Color: White
Shape: Elliptical / Oval

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: M L 17
Color: White
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: G L 10
Color: White
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: L612
Color: White
Shape: Elliptical / Oval

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: 5
Color: Blue
Shape: Round

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: M D17
Color: Red
Shape: Round

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: LU S71
Color: Blue
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: RC17
Color: White
Shape: Round

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: L5
Color: Blue
Shape: Round

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: SZ 302
Color: Blue
Shape: Round

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Drug: Loratadine
Strength: 5 Mg
Pill Imprint: D 5
Color: Blue
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: A-24
Color: White
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: A 24
Color: Orange
Shape: Round

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Drug: Loratadine
Strength: 10 Mg
Pill Imprint: A 24
Color: Pink
Shape: Round

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Drug: Loratadine
Strength: Loratadine 10 Mg
Pill Imprint: L612
Color: White
Shape: Elliptical / Oval

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