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Lyrica

Lyrica is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Lyrica is marketed by Pfizer under the trade name Lyrica. It is considered to have a dependence liability if misused, and is classified as a Schedule V drug in the U.S.

Lyrica is a new anticonvulsant drug indicated as an add on therapy for partial onset seizures and for certain types of neuropathic pain. It was designed as a more potent successor to a related drug, gabapentin. Lyrica binds to the alpha2-delta subunit of the voltage-gated calcium channel in the central nervous system. While lyrica is a structural derivative of the inhibitory neurotransmitter gamma- aminobutyric acid (GABA), it does not bind directly to GABAA, GABAB, or benzodiazepine receptors, does not augment GABAA responses in cultured neurons, does not alter rat brain GABA concentration or have acute effects on GABA uptake or degradation. However, in cultured neurons prolonged application of lyrica increases the density of GABA transporter protein and increases the rate of functional GABA transport. Lyrica does not block sodium channels, is not active at opiate receptors, and does not alter cyclooxygenase enzyme activity. It is inactive at serotonin and dopamine receptors and does not inhibit dopamine, serotonin, or noradrenaline reuptake.

Most common adverse reactions (≥5% and twice placebo) are dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and thinking abnormal (primarily difficulty with concentration/attention).

Imprints


Drug: Lyrica
Strength: 75 Mg
Pill Imprint: Pfizer PGN 75
Color: Orange & White
Shape: Capsule-shape

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Drug: Lyrica
Strength: 50 Mg
Pill Imprint: Pfizer PGN 50
Color: White
Shape: Capsule-shape

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Drug: Lyrica
Strength: 150 Mg
Pill Imprint: Pfizer PGN 150
Color: White
Shape: Capsule-shape

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Drug: Lyrica
Strength: 100 Mg
Pill Imprint: Pfizer PGN 100
Color: Orange
Shape: Capsule-shape

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Drug: Lyrica
Strength: 300 Mg
Pill Imprint: Pfizer PGN 300
Color: Orange & White
Shape: Capsule-shape

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Drug: Lyrica
Strength: 200 Mg
Pill Imprint: Pfizer PGN 200
Color: Orange
Shape: Capsule-shape

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Drug: Lyrica
Strength: 25 Mg
Pill Imprint: Pfizer PGN 25
Color: White
Shape: Capsule-shape

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Drug: Lyrica
Strength: 225 Mg
Pill Imprint: Pfizer PGN 225
Color: Orange & White
Shape: Capsule-shape

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