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Metformin

Metformin is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM ). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin may induce weight loss and is the drug of choice for obese NIDDM patients. Use of metformin is associated with modest weight loss. When used alone, metformin does not cause hypoglycemia; however, it may potentiate the hypoglycemic effects of sulfonylureas and insulin. Its main side effects are dyspepsia, nausea and diarrhea. Dose titration and/or use of smaller divided doses may decrease side effects. Metformin should be avoided in those with severely compromised renal function (creatinine clearance < 30 ml/min), acute/decompensated heart failure, severe liver disease and for 48 hours after the use of iodinated contrast dyes due to the risk of lactic acidosis. Lower doses should be used in the elderly and those with decreased renal function. Metformin decreases fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control. Metformin may also have a positive effect on lipid levels. In 2012, a combination tablet of linagliptin plus metformin hydrochloride was marketed under the name Jentadueto for use in patients when treatment with both linagliptin and metformin is appropriate.

Metformin is an oral antihyperglycemic agent that improves glucose tolerance in patients with NIDDM, lowering both basal and postprandial plasma glucose. Metformin is not chemically or pharmacologically related to any other class of oral antihyperglycemic agents. Unlike sulfonylureas, metformin does not produce hypoglycemia in either patients with NIDDM or healthy subjects and does not cause hyperinsulinemia. Metformin does not affect insulin secretion.

Acute oral toxicity (LD50): 350 mg/kg [Rabbit]. It would be expected that adverse reactions of a more intense character including epigastric discomfort, nausea, and vomiting followed by diarrhea, drowsiness, weakness, dizziness, malaise and headache might be seen.

Imprints


Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: M G 32
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: 93 7456
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: 93 7457
Color: Pink
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 2.5 Mg / 250 Mg
Pill Imprint: M G 31
Color: White
Shape: Round

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: U 786
Color: Pink
Shape: Capsule-shape

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Drug: Metformin
Strength: 2.5 Mg / 250 Mg
Pill Imprint: Cor 167
Color: Pink
Shape: Round

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: U 785
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: M G 33
Color: Beige
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: Cor 169
Color: Pink
Shape: Round

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Drug: Metformin
Strength: 2.5 Mg / 250 Mg
Pill Imprint: 93 7455
Color: Pink
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: Cor 168
Color: White
Shape: Round

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Drug: Metformin
Strength: 2.5 Mg / 250 Mg
Pill Imprint: U 787
Color: Pink
Shape: Capsule-shape

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: 724 C
Color: Peach
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 2.5 Mg / 250 Mg
Pill Imprint: 727 C
Color: Peach
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: 725 C
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: BMS 6060 500
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: 10 00 BMS 6071
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: BMS 6070 850
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: BMS 6063 500
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: BMS 6064 750
Color: Red
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: Logo 5712 5/500
Color: Yellow
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: A 48
Color: Yellow
Shape: Capsule-shape

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: Logo 5711 2.5/500
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: R 753
Color: Blue
Shape: Capsule-shape

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: A 47
Color: Pink
Shape: Capsule-shape

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: R 752
Color: Yellow
Shape: Capsule-shape

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Drug: Metformin
Strength: 1.25 Mg / 250 Mg
Pill Imprint: 6057
Color: Yellow
Shape: Capsule-shape

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: I 23
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1.25 Mg / 250 Mg
Pill Imprint: Logo 5710 1.25/250
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: I 24
Color: Yellow
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: 6059
Color: Yellow
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1.25 Mg / 250 Mg
Pill Imprint: Cor 140
Color: Yellow
Shape: Round

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: Cor 142
Color: Yellow
Shape: Round

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Drug: Metformin
Strength: 1.25 Mg / 250 Mg
Pill Imprint: A 46
Color: Yellow
Shape: Capsule-shape

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: Cor 141
Color: Orange
Shape: Round

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: 6058
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1.25 Mg / 250 Mg
Pill Imprint: R 751
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 1.25 Mg / 250 Mg
Pill Imprint: I 25
Color: Yellow
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 5 Mg / 500 Mg
Pill Imprint: 93 7262
Color: Yellow
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 2.5 Mg / 500 Mg
Pill Imprint: 7261 93
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1.25 Mg-250 Mg
Pill Imprint: 7260 93
Color: Yellow
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 93 48
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Z 70
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: A 12
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 397
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: Z 71
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: 93 72 14
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: A 1 4
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: G MF 1
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: GP 124
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: GP 128
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: MP 751
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: G G MF 3
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: H 104
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: I45
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: H 102
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 227
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: C 474
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Logo 4331 500
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: Z 69
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: 93 49
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: I 47
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: APO 500 MET
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: 435
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: IP 175 500
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: G 45 500
Color: White
Shape: Round

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: GP 127
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: IP 177 10 00
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 500 ANDRX 674
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: Logo 4432 10 00
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: A 13
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: G 45 1000
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: G MF 2
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: M 234
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: 10 00 Andrx 676
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: MP 752
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 2713 WPI
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: 228
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: M 244
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: Logo 4330 850
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: B 387 10 00
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: M 240
Color: White
Shape: Round

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: I46
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: RX860
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: APO 1000
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: H 103
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: MP 753
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: E 213
Color: White
Shape: Round

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: IP 176 850
Color: White
Shape: Round

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: 850 ANDRX 675
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: 229 229
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: B386 850
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: APO 850
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: B385 500
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: G 45 850
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: WPI WPI 2455
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: RX 767
Color: Pink
Shape: Capsule-shape

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: WPI 2775
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: APO M/500
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: Logo 1000
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Logo 500
Color: White
Shape: Round

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: Logo 850
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 142
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: IP 178
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 93 7267
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Logo 571 500
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: M 350
Color: Tan
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: IP 179
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: IP 218 500
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: APO XR500
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: IP 220 10 00
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: 143
Color: Red
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: E 4416
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: M 352
Color: Orange
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: 93 7212
Color: Red
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Logo 4435 500
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: Logo 577 750
Color: Yellow
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 500 6065
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: SG 106
Color: White
Shape: Round

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: APO XR750
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: Z C 20
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: IP 219 850
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: LU Q22
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg / 15 Mg (base)
Pill Imprint: MYLAN P155
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: B 107
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg / 15 Mg (base)
Pill Imprint: MYLAN P157
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Z 63
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 850 Mg / 15 Mg
Pill Imprint: 4833M 15 850
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg / 15 Mg
Pill Imprint: 4833M 15 500
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: LU Q21
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Logo 574
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: E 221
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: Logo 575
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: SG 105
Color: White
Shape: Round

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: R 728
Color: Orange
Shape: Capsule-shape

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: E 215
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: S G 1 07
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg / 15 Mg
Pill Imprint: TV 7677
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg / 15 Mg
Pill Imprint: TV 7678
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 4467 V
Color: White
Shape: Round

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: XR 750
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 134
Color: Green
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: 132
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: 131
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: 44 69 V
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: 4468 V
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: C 29
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: R R 718 718
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: P533 850
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Logo 500
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: NM7
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: P 535 10 00
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 001
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 850 Mg / 15 Mg (base)
Pill Imprint: SZ442
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg / 15 Mg (base)
Pill Imprint: 15/500 1280
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: NM5
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg / 15 Mg (base)
Pill Imprint: H 92
Color: White
Shape: Rectangle

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: R 657
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: A 19
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: P531 500
Color: White
Shape: Round

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Drug: Metformin
Strength: 750 Mg
Pill Imprint: Logo 750
Color: Red
Shape: Capsule-shape

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Drug: Metformin
Strength: 850 Mg / 15 Mg (base)
Pill Imprint: H 93
Color: White
Shape: Rectangle

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Drug: Metformin
Strength: 850 Mg / 15 Mg (base)
Pill Imprint: 15/850 1281
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg / 15 Mg (base)
Pill Imprint: SZ441
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Logo 001
Color: White
Shape: Capsule-shape

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: M MN2
Color: Pink
Shape: Round

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: R 715
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: M MN1
Color: Pink
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: R 740
Color: Yellow
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: G 10
Color: White
Shape: Round

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Drug: Metformin
Strength: 850 Mg
Pill Imprint: G 11
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: G 12
Color: White
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: Logo 575
Color: White
Shape: Round

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: 500 GMZ
Color: Blue
Shape: Elliptical / Oval

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Drug: Metformin
Strength: 500 Mg
Pill Imprint: Logo 574
Color: White
Shape: Round

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Drug: Metformin
Strength: 1000 Mg
Pill Imprint: M1000
Color: White
Shape: Elliptical / Oval

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