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Naloxone

A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.

Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the “agonistic” or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity. When given intravenously, the onset of action is apparent within 2 minutes. The onset of action is slower if given subcutaneously or intramuscularly. The duration of action also differs between sites of injection and dose.

LD50, IV administration, mouse = 150 ± 5 mg/kg; LD50, IV administration, rat = 109 ± 4 mg/kg;

Imprints


Drug: Naloxone
Strength: 0.5 Mg / 50 Mg
Pill Imprint: WATSON 395 50 0 .5
Color: Green
Shape: Elliptical / Oval

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Drug: Naloxone
Strength: 8 Mg (base) / 2 Mg (base)
Pill Imprint: AN 415
Color: Orange
Shape: Round

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Drug: Naloxone
Strength: 2 Mg (base) / 0.5 Mg (base)
Pill Imprint: A 14
Color: Orange
Shape: Round

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Drug: Naloxone
Strength: 0.5 Mg / 50 Mg
Pill Imprint: NL 680
Color: Yellow
Shape: Capsule-shape

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Drug: Naloxone
Strength: 0.5 Mg / 50 Mg
Pill Imprint: A211
Color: Yellow
Shape: Elliptical / Oval

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Drug: Naloxone
Strength: 2 Mg (base) / 0.5 Mg (base)
Pill Imprint: 54 122
Color: Peach
Shape: Round

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Drug: Naloxone
Strength: 8 Mg (base) / 2 Mg (base)
Pill Imprint: Logo (Actavis) 155
Color: White
Shape: Round

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Drug: Naloxone
Strength: 2 Mg (base) / 0.5 Mg (base)
Pill Imprint: Logo (Actavis) 154
Color: White
Shape: Round

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Drug: Naloxone
Strength: 8 Mg (base) / 2 Mg (base)
Pill Imprint: 54 375
Color: Peach
Shape: Round

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Drug: Naloxone
Strength: 2 Mg (base) / 0.5 Mg (base)
Pill Imprint: 93 B9
Color: White
Shape: Capsule-shape

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Drug: Naloxone
Strength: 8 Mg (base) / 2 Mg (base)
Pill Imprint: 93 5721
Color: White
Shape: Round

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