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Niaspan

A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP . It has pellagra-curative, vasodilating, and antilipemic properties.

Niaspan and niaspanamide are indicated for prevention and treatment of vitamin B3 deficiency states. Vitamin B3 (Niaspan) also acts to reduce LDL cholesterol, triglycerides, and HDL cholesterol. The magnitude of individual lipid and lipoprotein responses may be influenced by the severity and type of underlying lipid abnormality. The increase in total HDL is associated with a shift in the distribution of HDL subfractions (as defined by ultra-centrifugation) with an increase in the HDL2:HDL3 ratio and an increase in apolipoprotein A-I content. Vitamin B3 (Niaspan) treatment also decreases the serum levels of apolipoprotein B-100 (apo B), the major protein component of the VLDL (very low-density lipoprotein) and LDL fractions, and of lipoprotein-a, a variant form of LDL independently associated with coronary risk.

Nicotinic acid can cause vasodilation of cutaneous blood vessels resulting in increased blood flow, principally in the face, neck and chest. This produces the niaspan- or nicotinic acid-flush. The niaspan-flush is thought to be mediated via the prostaglandin prostacyclin. Histamine may also play a role in the niaspan-flush. Flushing is the adverse reaction first observed after intake of a large dose of nicotinic acid, and the most bothersome one. LD50 7000 mg/kg (Rat)

Imprints


Drug: Niaspan
Strength: 500 Mg
Pill Imprint: KOS 500
Color: Orange
Shape: Capsule-shape

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Drug: Niaspan
Strength: 500 Mg
Pill Imprint: A 500
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 1000 Mg
Pill Imprint: A 1000
Color: Orange
Shape: Elliptical / Oval

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Drug: Niaspan
Strength: 1000 Mg
Pill Imprint: KOS 1000
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 750 Mg
Pill Imprint: KOS 750
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 750 Mg
Pill Imprint: A 750
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 500 Mg
Pill Imprint: KOS 500
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 500 Mg
Pill Imprint: A 500
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 500 Mg
Pill Imprint: KOS 500
Color: White
Shape: Elliptical / Oval

View Images & Details

Drug: Niaspan
Strength: 1000 Mg
Pill Imprint: A 1000
Color: Orange
Shape: Elliptical / Oval

View Images & Details

Drug: Niaspan
Strength: 1000 Mg
Pill Imprint: KOS 1000
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 750 Mg
Pill Imprint: KOS 750
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 1000 Mg
Pill Imprint: KOS 1000
Color: White
Shape: Elliptical / Oval

View Images & Details

Drug: Niaspan
Strength: 750 Mg
Pill Imprint: A 750
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Niaspan
Strength: 750 Mg
Pill Imprint: KOS 750
Color: White
Shape: Elliptical / Oval

View Images & Details
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