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Norco

Narcotic analgesic related to codeine, but more potent and more addicting by weight. It is used also as cough suppressant.

Norco, a semisynthetic opiate agonist and hydrogenated ketone derivative, is similar to other phenanthrene derivatives, such as codeine. Used as an analgesic, norco is combined with acetaminophen, ibuprofen, or aspirin to treat pain. Used as an antitussive, norco is combined with phenylephrine, pseudoephedrine, phenylpropanolamine, guaifenesin, pyrilamine, pheniramine, or chlorpheniramine. Opiate agonists exert their principal pharmacologic effect at specific receptor binding sites in the CNS and other tissues. There are several subtypes of opiate receptors including the mu receptor (localized in pain modulating regions of the CNS), the kappa receptor (localized in the deep layers of the cerebral cortex), the delta receptor (localized in the limbic regions of the CNS), and the sigma receptor (thought to mediate the dysphoric and psychotomimetic effects of some opiate partial agonists). Agonist activity at the mu or kappa receptor can result in analgesia, miosis, and/or decreased body temperature. Agonist activity at the mu receptor can also result in suppression of opiate withdrawal, whereas antagonist activity can result in precipitation of withdrawal. Opiate agonists act at several sites within the CNS involving several systems of neurotransmitters to produce analgesia, but the precise mechanism of action has not been fully determined. Opiate agonists do not alter the threshold or responsiveness of afferent nerve endings to noxious stimuli nor the conduction of impulses along peripheral nerves. Instead, they alter the perception of pain at the spinal cord and higher levels in the CNS and the person’s emotional response to pain.

Symptoms of overdose include respiratory depression (a decrease in respiratory rate and/or tidal volume, Cheyne-Stokes respiration, cyanosis), extreme somnolence progressing to stupor or coma, skeletal muscle flaccidity, dizziness, ringing in the ears, confusion, blurred vision, eye problems, cold and clammy skin, and sometimes bradycardia and hypotension. In severe overdose, apnea, circulatory collapse, cardiac arrest and death may occur. LD50=85.7mg/kg (subcutaneous, in mice).

Imprints


Drug: Norco
Strength: 325 Mg / 10 Mg
Pill Imprint: NORCO 539
Color: Yellow
Shape: Elliptical / Oval

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Drug: Norco
Strength: 325 Mg / 5 Mg
Pill Imprint: WATSON 913
Color: White / Orange
Shape: Capsule-shape

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Drug: Norco
Strength: 325 Mg / 7.5 Mg
Pill Imprint: WATSON 729
Color: Orange
Shape: Elliptical / Oval

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Drug: Norco
Strength: 325 Mg / 7.5 Mg
Pill Imprint: NORCO 729
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Norco
Strength: 325 Mg / 10 Mg
Pill Imprint: NORCO 539
Color: White
Shape: Capsule-shape

View Images & Details

Drug: Norco
Strength: 325 Mg / 7.5 Mg
Pill Imprint: NORCO 729
Color: White
Shape: Capsule-shape

View Images & Details
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