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Nortriptyline

Nortriptyline hydrochloride, the N-demethylated active metabolite of amitriptyline, is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA ). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, nortriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, nortriptyline exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Secondary amine TCAs, such as nortriptyline, are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline. TCAs also down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Nortriptyline exerts less anticholinergic and sedative side effects compared to the tertiary amine TCAs, amitriptyline and clomipramine. Nortriptyline may be used to treat depression, chronic pain (unlabeled use), irritable bowel syndrome (unlabeled use), diabetic neuropathy (unlabeled use), post-traumatic stress disorder (unlabeled use), and for migraine prophylaxis (unlabeled use).

Similar to protriptyline, nortriptyline is a tricyclic antidepressant of the dibenzocycloheptene type and is the active metabolite of amitriptyline.

Symptoms of overdose include cardiac dysrhythmias, severe hypotension, shock, congestive heart failure, pulmonary edema, convulsions, and CNS depression, including coma. Changes in the electrocardiogram, particularly in QRS axis or width, are clinically significant indicators of tricyclic antidepressant toxicity. Side effects include: sedation, hypotension, blurred vision, dry mouth, constipation, urinary retention, postural hypotension, tachycardia, hypertension, ECG changes, heart failure, impaired memory and delirium, and precipitation of hypomanic or manic episodes in bipolar depression. Withdrawal symptoms include gastrointestinal disturbances, anxiety, and insomnia.

Imprints


Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: NORTRIPTYLINE DAN 25 Mg
Color: Green & White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: TEVA 25 Mg 0811
Color: Orange & White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: TEVA 10 Mg 0810
Color: Orange & White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: 93 811 93 811
Color: Orange & White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: NORTIPTYLINE DAN 10 Mg
Color: Green & White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: TEVA 50 Mg 0812
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: 93 810 93 810
Color: Orange / White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 75 Mg
Pill Imprint: 93 813 93 813
Color: Orange
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: NORTRIPTYLINE DAN 50 Mg
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 75 Mg
Pill Imprint: TEVA 75 Mg 0813
Color: Orange
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: 10 Mg 93 810
Color: Orange / White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: 25 Mg 93 811
Color: White / Orange
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 75 Mg
Pill Imprint: NORTRIPTYLINE 75 Mg 253 Cp
Color: Green
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: NORTRIPTYLINE 50 Mg 252 Cp
Color: Green / Yellow
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: MYLAN 3250 MYLAN 3250
Color: Red & Yellow
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: 93 812 93 812
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: MYLAN 1410 MYLAN 1410
Color: Red
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: GG 567 GG 567
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 75 Mg
Pill Imprint: TARO NTP 75
Color: Green
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: 50 Mg 93 812
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 75 Mg
Pill Imprint: NORTRIPTYLINE DAN 75 Mg
Color: Green
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: TARO NTP 50
Color: Green & White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 75 Mg
Pill Imprint: MYLAN 4175 MYLAN 4175
Color: Brown & Orange
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: MYLAN 2325 MYLAN 2325
Color: Red / Orange
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: TARO NTP 25
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: GG 566 GG 566
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 75 Mg
Pill Imprint: 75 Mg 93 813
Color: Orange
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: TARO NTP 10
Color: Green
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 MG
Pill Imprint: GG 565
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: 251 NORTRIPTYLINE 25
Color: Green & White
Shape:

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: 250 NORTRIPTYLINE 10
Color: Green & White
Shape:

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: NORTRIPTYLINE DAN 10 Mg
Color: Green / White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: Logo PAMELOR 25 Mg Logo SANDOZ
Color: Orange / White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: Logo PAMELOR 10 Mg Logo SANDOZ
Color: Orange / White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 25 Mg
Pill Imprint: PAMELOR 25 Mg M
Color: Orange & White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: Logo PAMELOR 50 Mg Logo SANDOZ
Color: White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 10 Mg
Pill Imprint: PAMELOR 10 Mg M
Color: Orange & White
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 75 Mg
Pill Imprint: PAMELOR 75 Mg M
Color: Orange
Shape: Capsule-shape

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Drug: Nortriptyline
Strength: 50 Mg
Pill Imprint: PAMELOR 50 Mg M
Color: White
Shape: Capsule-shape

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