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Ondansetron

A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors. The serontonin 5-HT3 receptors are located on the nerve terminals of the vagus in the periphery, and centrally in the chemoreceptor trigger zone of the area postrema. The temporal relationship between the emetogenic action of emetogenic drugs and the release of serotonin, as well as the efficacy of antiemetic agents suggest that chemotherapeutic agents release serotonin from the enterochromaffin cells of the small intestine by causing degenerative changes in the GI tract. The serotonin then stimulates the vagal and splanchnic nerve receptors that project to the medullary vomiting center, as well as the 5-HT3 receptors in the area postrema, thus initiating the vomiting reflex, causing nausea and vomiting.

Low blood pressure and fainting, sudden blindness, severe constipation

Imprints


Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: R 153
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: R 154
Color: Yellow
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: M 732
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: NO 4
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: 93 233
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: M 315
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: M 734
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: NO 8
Color: Yellow
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: M 344
Color: Orange
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: 130
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: 93 7236
Color: Yellow
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: G1 4
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: GG 927
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: GG 928
Color: Yellow
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: 131
Color: Yellow
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: G1 8
Color: Yellow
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: F 91
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: PL OND 4
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: F 92
Color: Yellow
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: PL OND 8
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: W 04
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: 04
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 24 Mg
Pill Imprint: R 156
Color: Pink
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: WW 12
Color: Yellow
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: 08
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: E 363
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 24 Mg
Pill Imprint: WW 24
Color: Pink
Shape: Capsule-shape

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: E 364
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: G 4
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: ON 4
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: K 2
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: SZ 342
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: ON 8
Color: Yellow
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: G 8
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: K 1
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: SZ 343
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: E 5
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: 93 7301
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: E 7
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: 93 7302
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: 240
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: 241
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: APO OND4
Color: White
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: APO OND8
Color: Yellow
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 24 Mg
Pill Imprint: G1 24
Color: Pink
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 24 Mg
Pill Imprint: TARO OND24
Color: Pink
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 24 Mg
Pill Imprint: GG 305
Color: Pink
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: RE6
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 4 Mg
Pill Imprint: TARO OND4
Color: Yellow
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 24 Mg
Pill Imprint: C 71
Color: Pink
Shape: Elliptical / Oval

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: RE7
Color: White
Shape: Round

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Drug: Ondansetron
Strength: 8 Mg
Pill Imprint: TARO OND8
Color: White
Shape: Elliptical / Oval

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