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Prozac

Prozac hydrochloride is the first agent of the class of antidepressants known as selective serotonin-reuptake inhibitors (SSRIs). Prozac is a racemic mixture of the R- and S- enantiomers and are of equivalent pharmacologic activity. Despite distinct structural differences between compounds in this class, SSRIs possess similar pharmacological activity. As with other antidepressant agents, several weeks of therapy may be required before a clinical effect is seen. SSRIs are potent inhibitors of neuronal serotonin reuptake. They have little to no effect on norepinephrine or dopamine reuptake and do not antagonize α- or β-adrenergic, dopamine D2 or histamine H1 receptors. During acute use, SSRIs block serotonin reuptake and increase serotonin stimulation of somatodendritic 5-HT1A and terminal autoreceptors. Chronic use leads to desensitization of somatodendritic 5-HT1A and terminal autoreceptors. The overall clinical effect of increased mood and decreased anxiety is thought to be due to adaptive changes in neuronal function that leads to enhanced serotonergic neurotransmission. Side effects include dry mouth, nausea, dizziness, drowsiness, sexual dysfunction and headache. Side effects generally occur within the first two weeks of therapy and are usually less severe and frequent than those observed with tricyclic antidepressants. Prozac may be used to treat major depressive disorder (MDD ), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD ), premenstrual dysphoric disorder (PMDD ), panic disorder with or without agoraphobia, and in combination with olanzapine for treatment-resistant or bipolar I depression. Prozac is the most anorexic and stimulating SSRI .

Prozac, an antidepressant agent belonging to the selective serotonin reuptake inhibitors (SSRIs), is used to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress. According to the amines hypothesis, a functional decrease in the activity of amines, such as serotonin and norepinephrine, would result in depression; a functional increase of the activity of these amines would result in mood elevation. Prozac’s effects are thought to be associated with the inhibition of 5HT receptor, which leads to an increase of serotonin level. Antagonism of muscarinic, histaminergic, and α1–adrenergic receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects of classical tricyclic antidepressant (TCA) drugs. Prozac binds to these and other membrane receptors from brain tissue much less potently in vitro than do the tricyclic drugs.

Symptoms of overdose include agitation, restlessness, hypomania, and other signs of CNS excitation. LD50=284mg/kg (orally in mice). The most frequent side effects include: nervous system effects such as anxiety, nervousness, insomnia, drowsiness, fatigue or asthenia, tremor, and dizziness or lightheadedness; GI effects such as anorexia, nausea, and diarrhea; vasodilation; dry mouth; abnormal vision; decreased libido; abnormal ejaculation; rash; and sweating. Withdrawal symptoms include flu-like symptoms, insomnia, nausea, imbalance, sensory changes and hyperactivity.

Imprints


Drug: Prozac
Strength: 20 Mg
Pill Imprint: DISTA 3105 PROZAC 20 Mg
Color: Green & Yellow
Shape: Capsule-shape

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Drug: Prozac
Strength: 10 Mg
Pill Imprint: PROZAC 10
Color: Green
Shape: Elliptical / Oval

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Drug: Prozac
Strength: 40 Mg
Pill Imprint: DISTA 3107 PROZAC 40mg
Color: Green & Orange
Shape: Capsule-shape

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Drug: Prozac
Strength: 90 MG
Pill Imprint: 3004 90mg Lilly
Color: Green / Clear
Shape: Capsule-shape

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Drug: Prozac
Strength: 10 Mg
Pill Imprint: DISTA 3104 PROZAC 10 Mg
Color: Green
Shape: Capsule-shape

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Drug: Prozac
Strength: 20 Mg
Pill Imprint: DISTA 3105 PROZAC 20 Mg
Color: Green & Yellow
Shape: Capsule-shape

View Images & Details

Drug: Prozac
Strength: 10 Mg
Pill Imprint: PROZAC 10
Color: Green
Shape: Elliptical / Oval

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Drug: Prozac
Strength: 40 Mg
Pill Imprint: DISTA 3107 PROZAC 40mg
Color: Green & Orange
Shape: Capsule-shape

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Drug: Prozac
Strength: 10 Mg
Pill Imprint: DISTA 3104 PROZAC 10 Mg
Color: Green
Shape: Capsule-shape

View Images & Details
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