866-897-8297

Call Is Confidential & Toll Free

Ramipril

Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE ) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE , the enzyme responsible for the conversion of angiotensin I (ATI ) to angiotensin II (ATII ). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ). Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular events.

Ramipril is an ACE inhibitor similar to benazepril, fosinopril and quinapril. It is an inactive prodrug that is converted to ramiprilat in the liver, the main site of activation, and kidneys. Ramiprilat confers blood pressure lowing effects by antagonizing the effect of the RAAS. The RAAS is a homeostatic mechanism for regulating hemodynamics, water and electrolyte balance. During sympathetic stimulation or when renal blood pressure or blood flow is reduced, renin is released from the granular cells of the juxtaglomerular apparatus in the kidneys. In the blood stream, renin cleaves circulating angiotensinogen to ATI, which is subsequently cleaved to ATII by ACE. ATII increases blood pressure using a number of mechanisms. First, it stimulates the secretion of aldosterone from the adrenal cortex. Aldosterone travels to the distal convoluted tubule (DCT) and collecting tubule of nephrons where it increases sodium and water reabsorption by increasing the number of sodium channels and sodium-potassium ATPases on cell membranes. Second, ATII stimulates the secretion of vasopressin (also known as antidiuretic hormone or ADH) from the posterior pituitary gland. ADH stimulates further water reabsorption from the kidneys via insertion of aquaporin-2 channels on the apical surface of cells of the DCT and collecting tubules. Third, ATII increases blood pressure through direct arterial vasoconstriction. Stimulation of the Type 1 ATII receptor on vascular smooth muscle cells leads to a cascade of events resulting in myocyte contraction and vasoconstriction. In addition to these major effects, ATII induces the thirst response via stimulation of hypothalamic neurons. ACE inhibitors inhibit the rapid conversion of ATI to ATII and antagonize RAAS-induced increases in blood pressure. ACE (also known as kininase II) is also involved in the enzymatic deactivation of bradykinin, a vasodilator. Inhibiting the deactivation of bradykinin increases bradykinin levels and may sustain the effects of ramiprilat by causing increased vasodilation and decreased blood pressure.

Symptoms of overdose may include excessive peripheral vasodilation (with marked hypotension and shock), bradycardia, electrolyte disturbances, and renal failure. The most likely adverse reactions are symptoms attributable to its blood-pressure lowing effect. May cause headache, dizziness, asthenia, chest pain, nausea, peripheral edema, somnolence, impotence, rash, arthritis, and dyspnea. LD50 = 10933 mg/kg (orally in mice).

Imprints


Drug: Ramipril
Strength: 10 Mg
Pill Imprint: LUPIN RAMIPRIL 10mg
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: > RP 10
Color: White / Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: > RP 5
Color: White / Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: GG 650 10mg
Color: Blue & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: LUPIN RAMIPRIL 5mg
Color: Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: 54 602 54 602
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: 54 145 54 145
Color: Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: LUPIN RAMIPRIL 2.5mg
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: APO 10
Color: Blue & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: 54 794 54 794
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: APO 5
Color: Red & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: RP 2.5 >
Color: Orange & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: 93 7438 93 7438
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: APO 2.5
Color: Orange & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: RP 1.25 >
Color: White & Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: LUPIN RAMIPRIL 1.25mg
Color: Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: APO 1.25
Color: Yellow & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: IG 273 5 Mg
Color: Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: ZA-45 5 Mg
Color: Red & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: ZA-46 10 Mg
Color: Blue & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: IG 274 10mg
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: 0145 2.5 Mg
Color: Orange & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: 93 7437 93 7437
Color: Pink
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: RDY 438
Color: Yellow & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: 0146 5 Mg
Color: Red & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: GG 649 5mg
Color: Red & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: 54 328 54 328
Color: Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: IG 272 2.5mg
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: 0147 10 Mg
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: ZA-44 2.5 Mg
Color: Orange & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: 93 7436 93 7436
Color: Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: D 08
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: RDY 441
Color: Blue & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: GG 648 2.5mg
Color: Orange & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: 0144 1.25 Mg
Color: White & Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: D 07
Color: Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: ZA-43 1.25 Mg
Color: Yellow & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: RDY 439
Color: Orange & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: IG 271 1.25mg
Color: Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: GG 647 GG 647
Color: White & Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: RDY 440
Color: Orange & White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: R2696
Color: Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: R2695
Color: White
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: D 06
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: D 05
Color: Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: R2697
Color: Gray
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: RA31 RA31
Color: Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: RA32 RA32
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: RAM 1.25 Mg
Color: Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: RAM 2.5 Mg
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: RAM 5 Mg
Color: Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: RAM 10 Mg
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: ALTACE 10mg MP
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: ALTACE 2.5mg MP
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: ALTACE 5mg MP
Color: Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: ALTACE 5 Mg HOECHST
Color: Red
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: ALTACE 10 MG HOECHST
Color: Blue
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: ALTACE 1.25 Mg MP
Color: Yellow
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: ALTACE 2.5 Mg HOECHST
Color: Orange
Shape: Capsule-shape

View Images & Details

Drug: Ramipril
Strength: 10 Mg
Pill Imprint: AL10
Color: Blue
Shape: Elliptical / Oval

View Images & Details

Drug: Ramipril
Strength: 1.25 Mg
Pill Imprint: AL1.25
Color: White
Shape: Elliptical / Oval

View Images & Details

Drug: Ramipril
Strength: 2.5 Mg
Pill Imprint: AL2.5
Color: Orange
Shape: Elliptical / Oval

View Images & Details

Drug: Ramipril
Strength: 5 Mg
Pill Imprint: AL5
Color: Red
Shape: Elliptical / Oval

View Images & Details
Disclaimer: We strive to ensure that the content on pilladdictions.com is current and factual at the time it was written. However, because new information and discoveries are always becoming available, we are not making any representations or warranties with respect to this content. Please always rely on the guidance of your physician for information about the drugs you are taking and the impacts they may or may not have on your health.

Questions About Prescription Drug Addiction?

(888) 740-2069

Questions About Prescription Drug Addiction?