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Sensipar

Sensipar (INN ) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues. It is sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. Sensipar is used to treat hyperparathyroidism (elevated parathyroid hormone levels), a consequence of parathyroid tumors and chronic renal failure.

Sensipar is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues). Secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) is a progressive disease, associated with increases in parathyroid hormone (PTH) levels and derangements in calcium and phosphorus metabolism. Increased PTH stimulates osteoclastic activity resulting in cortical bone resorption and marrow fibrosis. The goals of treatment of secondary hyperparathyroidism are to lower levels of PTH, calcium, and phosphorus in the blood, in order to prevent progressive bone disease and the systemic consequences of disordered mineral metabolism. In CKD patients on dialysis with uncontrolled secondary HPT, reductions in PTH are associated with a favorable impact on bone-specific alkaline phosphatase (BALP), bone turnover and bone fibrosis. Sensipar reduces calcium levels by increasing the sensitivity of the calcium sensing receptor to extracellular calcium.

Doses titrated up to 300 mg once daily have been safely administered to patients on dialysis. Overdosage of sensipar may lead to hypocalcemia.

Imprints


Drug: Sensipar
Strength: 30 Mg
Pill Imprint: AMGEN 30
Color: Green
Shape: Elliptical / Oval

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Drug: Sensipar
Strength: 60 Mg
Pill Imprint: AMGEN 60
Color: Green
Shape: Elliptical / Oval

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Drug: Sensipar
Strength: 30 Mg
Pill Imprint: AMG 30
Color: Green
Shape: Elliptical / Oval

View Images & Details

Drug: Sensipar
Strength: 90 Mg
Pill Imprint: AMGEN 90
Color: Green
Shape: Elliptical / Oval

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Drug: Sensipar
Strength: 60 Mg
Pill Imprint: AMG 60
Color: Green
Shape: Elliptical / Oval

View Images & Details

Drug: Sensipar
Strength: 90 Mg
Pill Imprint: AMG 90
Color: Green
Shape: Elliptical / Oval

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