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Septra

A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by sulfonamides and the septra-sulfamethoxazole combination is the form most often used. It is sometimes used alone as an antimalarial. Septra resistance has been reported.

Septra is a pyrimidine analogue that disrupts folate synthesis, an essential part of the thymidine synthesis pathway. Inhibition of the enzyme starves the bacteria of nucleotides necessary for DNA replication.The drug, therefore, exhibits bactericidal activity.

LD50=4850 (orally in mice)

Imprints


Drug: Septra
Strength: 400 Mg / 80 Mg
Pill Imprint: SEPTRA M052
Color: Pink
Shape: Round

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Drug: Septra
Strength: 800 Mg / 160 Mg
Pill Imprint: SEPTRA DS O2C
Color: Pink
Shape: Elliptical / Oval

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Drug: Septra
Strength: 800 Mg / 160 Mg
Pill Imprint: SEPTRA DS M053
Color: Pink
Shape: Elliptical / Oval

View Images & Details
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