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Topamax

Topamax (brand name Topamax) is an anticonvulsant drug produced by Ortho-McNeil Neurologics, a division of Johnson & Johnson. It is used to treat epilepsy in both children and adults. In children it is also indicated for treatment of Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). It is also Food and Drug Administration (FDA ) approved for, and now most frequently prescribed for, the prevention of migraines. . A combination product containing phentermine and topamax extended-release called QSYMIA® is indicated for the management of obesity. On August 2013, an extended released formulation, marketed as Trokendi XR has been approved for the management of partial onset, tonic-clonic, and Lennox-Gastaut Syndrome seizures.

Topamax is an anticonvulsant indicated in the treatment of epilepsy and migraine. Topamax enhances GABA-activated chloride channels. In addition, topamax inhibits excitatory neurotransmission, through actions on kainate and AMPA receptors. There is evidence that topamax has a specific effect on GluR5 kainate receptors. It is also an inhibitor of carbonic anhydrase, particular subtypes II and IV, but this action is weak and unlikely to be related to its anticonvulsant actions, but may account for the bad taste and the development of renal stones seen during treatment. Its possible effect as a mood stabilizer seems to occur before anticonvulsant qualities at lower dosages. Topamax inhibits maximal electroshock and pentylenetetrazol-induced seizures as well as partial and secundarily generalized tonic-clonic seizures in the kindling model, findings predective of a broad spectrum of antiseizure activities clinically.

Symptoms of overdose include abdominal pain, agitation, blurred vision, convulsions, depression, dizziness, double vision, drowsiness, impaired coordination, impaired mental activity, low blood pressure, reduced consciousness, severe diarrhea, sluggishness, and speech problems.

Imprints


Drug: Topamax
Strength: 25 Mg
Pill Imprint: TOP 25
Color: White
Shape: Round

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Drug: Topamax
Strength: 100 Mg
Pill Imprint: TOPAMAX 100
Color: Yellow
Shape: Round

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Drug: Topamax
Strength: 50 Mg
Pill Imprint: TOPAMAX 50
Color: Yellow
Shape: Round

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Drug: Topamax
Strength: 200 Mg
Pill Imprint: TOPAMAX 200
Color: Orange
Shape: Round

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Drug: Topamax
Strength: 50 Mg
Pill Imprint: OMN 50
Color: Yellow
Shape: Round

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Drug: Topamax
Strength: 25 Mg
Pill Imprint: OMN 25
Color: White
Shape: Round

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Drug: Topamax
Strength: 100 Mg
Pill Imprint: OMN 100
Color: Yellow
Shape: Round

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Drug: Topamax
Strength: 200 Mg
Pill Imprint: OMN 200
Color: Peach
Shape: Round

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Drug: Topamax
Strength: 25 Mg
Pill Imprint: TOP 25 Mg
Color: White
Shape: Capsule-shape

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Drug: Topamax
Strength: 15 Mg
Pill Imprint: TOP 15 Mg
Color: White
Shape: Capsule-shape

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