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Ventolin

Ventolin is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD . It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Ventolin is formulated as a racemic mixture of the R- and S-isomers. The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer has been associated with toxicity. This lead to the development of levalbuterol, the single R-isomer of ventolin. However, the high cost of levalbuterol compared to ventolin has deterred wide-spread use of this enantiomerically pure version of the drug. Ventolin is generally used for acute episodes of bronchospasm caused by bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders such as chronic obstructive pulmonary disorder (COPD ). It is also used prophylactically for exercise-induced asthma.

Ventolin (INN) or albuterol (USAN), a moderately selective beta(2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity. The R-enantiomer is sold in its pure form as Levalbuterol. The manufacturer of levalbuterol, Sepracor, has implied (although not directly claimed) that the presence of only the R-enantiomer produces fewer side-effects.

LD50=1100 mg/kg (orally in mice)

Imprints


Drug: Ventolin
Strength: 2 MG
Pill Imprint: GLAXO GLAXO VENTOLIN 2
Color: White
Shape: Round

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Drug: Ventolin
Strength: 4 MG
Pill Imprint: GLAXO GLAXO VENTOLIN 4
Color: White
Shape: Round

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Drug: Ventolin
Strength: 2 MG
Pill Imprint: GLAXO GLAXO VENTOLIN 2
Color: White
Shape: Round

View Images & Details

Drug: Ventolin
Strength: 4 MG
Pill Imprint: GLAXO GLAXO VENTOLIN 4
Color: White
Shape: Round

View Images & Details
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